According to a study at the University of California in San Diego, USA, with 263 participants daily cannabis use was associated with reduced inflammation of the brain. They analysed data of 4 groups: HIV negative non-cannabis users (n = 65), HIV positive non-cannabis users (n = 105), HIV positive moderate cannabis users (n = 62), and HIV positive daily cannabis users (n = 31).

HIV positive daily cannabis users showed significant lower amounts of markers for inflammation in the cerebral spinal fluid compared to HIV positive non-cannabis users. Blood biomarkers showed no differences by cannabis use. Authors concluded that “current daily cannabis use was associated with lower levels of pro-inflammatory chemokines implicated in HIV pathogenesis and these chemokines were linked to the cognitive domain of learning.”

https://pubmed.ncbi.nlm.nih.gov/34261550/